AIG1 — Androgen induced 1
AIG1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AIG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Proliferation/differentiation Cell cycle | AKAP7, CCND1, DTX1, KLF4, SUSD4, TLR5, ZNF827 | View in SCUBA |
| Enterocytes | Long-gene nuclear transcripts Technical artifact | ABO, ATRN, CACNB2, FOXN3, IMMP2L, KCNJ3, PLA2R1, TIAM2 | View in SCUBA |
| Macrophages | Efferocytosis Anti-inflammatory Lysosomal & pahgocytosis | ABHD12, ADGRG5, AXL, CCS, CD101, CD1D, CD300A, EVA1B +18 more | View in SCUBA |
About the gene
| Synonyms | AIG-1, dJ95L4.1, FLJ10485 |
|---|---|
| Chromosome | 6: 143060496-143341058 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | Hydrolase |
| Biological process | Lipid metabolism |
Function
Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids. Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.