CCS — Copper chaperone for superoxide dismutase
CCS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Efferocytosis Anti-inflammatory Lysosomal & pahgocytosis | ABHD12, ADGRG5, AIG1, AXL, CD101, CD1D, CD300A, EVA1B +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARFRP1, ARL2, ATP6V0E1, CALHM2, COA4, DBP, DENND2D, DMAC1 +15 more |
About the gene
| Chromosome | 11: 66593153-66606019 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Chaperone |
Function
Delivers copper to copper zinc superoxide dismutase (SOD1)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.