ALDH7A1 — Aldehyde dehydrogenase 7 family member A1
ALDH7A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDH7A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | NF-κB Oxidative Stress Stress | ACP1, ARHGDIB, CCDC85C, CDC25B, CDKN3, CMSS1, COPRS, CYTL1 +13 more | View in SCUBA |
About the gene
| Synonyms | ATQ1, EPD, PDE |
|---|---|
| Chromosome | 5: 126531200-126595362 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.