ARHGDIB — Rho GDP dissociation inhibitor beta
ARHGDIB belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGDIB's module in each cell type
About the gene
| Synonyms | GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2 |
|---|---|
| Chromosome | 12: 14942031-14961728 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates reorganization of the actin cytoskeleton mediated by Rho family members.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.