ACP1 — Acid phosphatase 1
ACP1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | NF-κB Oxidative Stress Stress | ALDH7A1, ARHGDIB, CCDC85C, CDC25B, CDKN3, CMSS1, COPRS, CYTL1 +13 more | View in SCUBA |
| Fibroblasts | Actin Cytoskeletal Organization Cytoskeletal | AKR7A2, ARL3, CAPZB, DERL1, GDE1, LEPROTL1, LIMS1, NPTN +8 more | View in SCUBA |
| Innate lymphoid cells | Proteasome & TCA Protein processing & ER | ARPC5L, CAPZA1, CLTA, COPS9, HDAC1, MDH2, NDUFA1, NUDT16L1 +5 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ARPC5L, ATP6V1G1, AURKAIP1, C19orf53, CHMP2A, CIAO2B, CIB1, COPE +31 more | View in SCUBA |
About the gene
| Synonyms | HAAP, LMW-PTP, LMWPTP |
|---|---|
| Chromosome | 2: 264140-278283 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Protein phosphatase |
Function
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2. Does not possess phosphatase activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.