AMHR2 — Anti-Mullerian hormone receptor type 2
AMHR2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AMHR2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | HPC Stemness Program Stemness | ARMC8, CASP3, CITED2, CNRIP1, CSF2RB, DLC1, FBXO7, HBS1L +3 more |
About the gene
| Synonyms | MISR2, MISRII |
|---|---|
| Chromosome | 12: 53423855-53431672 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Kinase, Receptor, Serine/threonine-protein kinase, Transferase |
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.