ARMC8 — Armadillo repeat containing 8
ARMC8 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARMC8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | HPC Stemness Program Stemness | AMHR2, CASP3, CITED2, CNRIP1, CSF2RB, DLC1, FBXO7, HBS1L +3 more | |
| Macrophages | RAB-mediated Trafficking Vesicular traficking | ABI1, ACSL3, CACUL1, CD86, CHST15, CRTC3, CTNNA1, CUL4A +27 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434A043, GID5, HSPC056, VID28 |
|---|---|
| Chromosome | 3: 138187248-138298384 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.