SCUBA

ANGPTL6 — Angiopoietin like 6

ANGPTL6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ANGPTL6's module in each cell type

Cell typeModuleShares the module with
FibroblastsLamina Propria ECM
ECM production
ADAMTS7, ADGRL4, BMP2, CBLN2, CYTL1, DHRS7C, FAM135B, FBN2 +14 moreView in SCUBA

About the gene

SynonymsAGF, ARP5
Chromosome19: 10092338-10102678
Predicted locationSecreted
Essential geneNo
Protein classPlasma proteins, Predicted secreted proteins
Molecular functionDevelopmental protein
Biological processAngiogenesis, Differentiation

Function

May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.