ADGRL4 — Adhesion G protein-coupled receptor L4
ADGRL4 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADGRL4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Angiogenic Identity Endothelial cell development | ACTN4, APBB2, CAVIN1, CD93, CLEC14A, CLIC4, ESAM, MYH9 +5 more | View in SCUBA |
| Fibroblasts | Lamina Propria ECM ECM production | ADAMTS7, ANGPTL6, BMP2, CBLN2, CYTL1, DHRS7C, FAM135B, FBN2 +14 more | View in SCUBA |
About the gene
| Synonyms | ELTD1, ETL |
|---|---|
| Chromosome | 1: 78889764-79282124 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Endothelial orphan receptor that acts as a key regulator of angiogenesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.