ARHGAP6 — Rho GTPase activating protein 6
ARHGAP6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Megakaryocyte Commitment Myeloid development | C2orf88, CLU, ITGA2B, MPIG6B, PPP1R14A, PRKAR2B, RGS10, RGS18 +1 more |
About the gene
| Synonyms | rhoGAPX-1 |
|---|---|
| Chromosome | X: 11117651-11665920 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.