PRKAR2B — Protein kinase cAMP-dependent type II regulatory subunit beta
PRKAR2B belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRKAR2B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Hypoxia Tissue Adaptation Tissue residence | ABCB1, ADAMTS17, ANKRD28, CCRL2, EPAS1, FAM3C, KLHL6, LDLRAD4 +10 more | |
| Hematopoietic progenitor cells | Megakaryocyte Commitment Myeloid development | ARHGAP6, C2orf88, CLU, ITGA2B, MPIG6B, PPP1R14A, RGS10, RGS18 +1 more | |
| Natural Killer cells | Gut-Homing NK Gut residency | CCR9, FAM3C, GRAMD2B, OXNAD1, PLPP1, SMIM3, SNX9, TRAT1 | View in SCUBA |
| Smooth muscle cells | Netrin Guidance Signaling Development | GNG7, MMP23B, NTN1, PFKP, QSOX1, TMTC2, TYRP1 | View in SCUBA |
About the gene
| Synonyms | PRKAR2 |
|---|---|
| Chromosome | 7: 107044705-107161811 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.