ATP8B2 — ATPase phospholipid transporting 8B2
ATP8B2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATP8B2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Mucosal-associated invariant T cell | IL-12 Cytotoxic Effector cytotoxicity | ANKZF1, CD84, CTSH, DIP2A, HERC2, IL12RB1, LPCAT4, MBOAT1 +7 more |
About the gene
| Synonyms | ATPID, KIAA1137 |
|---|---|
| Chromosome | 1: 154325525-154351304 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Translocase |
| Biological process | Lipid transport, Transport |
Function
Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. May contribute to the maintenance of membrane lipid asymmetry
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.