BANK1 — B cell scaffold protein with ankyrin repeats 1
BANK1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BANK1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | MHC-I Antigen Presentation Anti-viral | B2M, CD48, CYSLTR1, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F +1 more | View in SCUBA |
About the gene
| Synonyms | BANK, FLJ20706 |
|---|---|
| Chromosome | 4: 101411286-102074812 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | B-cell activation |
Function
Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.