BIK — BCL2 interacting killer
BIK belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BIK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Chromatin Regulation DNA/chromatin regulation | DSTN, GCHFR, GRHPR, HDAC1, HMGN1, IMP4, LYPLA1, METAP2 +3 more | View in SCUBA |
About the gene
| Synonyms | NBK |
|---|---|
| Chromosome | 22: 43110750-43129712 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Apoptosis |
Function
Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.