CTSE — Cathepsin E
CTSE belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CTSE's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | BEST4 Colonocyte Identity Epithelial development | ACP5, ADCY7, ADGRE5, ATP2B4, C1orf21, CCPG1, CD276, GALNT6 +17 more | View in SCUBA |
About the gene
| Chromosome | 1: 206008535-206023909 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Aspartyl protease, Hydrolase, Protease |
Function
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.