CCPG1 — Cell cycle progression 1
CCPG1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCPG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Chromatin Cell Cycle DNA/chromatin regulation | ARPP19, BRD7, CMPK1, IPO9, MBD2, PDS5B, TM9SF2 | View in SCUBA |
| Gamma-delta T cells | SR Kinase & RNA RNA processing & translation | ADHFE1, ATF2, BCAP31, C4orf3, CHKB, CLK2, EFR3A, FASTK +17 more | |
| Neutrophils | NET Priming State Netosis | ADD3, APMAP, ARG1, CCDC125, ITGAM, PADI4, PLBD1, PPP2R5A +1 more |
About the gene
| Synonyms | CPR8, KIAA1254 |
|---|---|
| Chromosome | 15: 55340032-55408510 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell cycle |
Function
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.