CXCL14 — C-X-C motif chemokine ligand 14
CXCL14 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CXCL14's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Pericytes | BMP-Stromal Signaling Developmental | BMP4, F3, MMP2, NBL1, PDGFRA, POSTN, TMEM176A, TMEM176B | View in SCUBA |
About the gene
| Synonyms | BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14 |
|---|---|
| Chromosome | 5: 135570679-135579279 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Cytokine |
| Biological process | Chemotaxis |
Function
Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.