TMEM176B — Transmembrane protein 176B
TMEM176B belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEM176B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Myeloid Contamination Cell contamination | BASP1, C7, CARMIL1, CCL23, CH25H, CSRP2, CTSC, DENND2D +20 more | View in SCUBA |
| Enterocytes | Metallothionein metal response Stress | BLVRB, MT1E, MT1F, MT1G, MT1H, MT1M, MT1X, MT2A +1 more | View in SCUBA |
| Glial cells | Glial Myelination Identity Myelination | AP1S2, CALM2, CD81, CD9, COMT, GPM6B, GSN, IGFBP7 +6 more | View in SCUBA |
| Goblet cells | Epithelial Membrane Identity Epithelial development | EIF3H, EPCAM, ITM2B, PDLIM1, RAC1, SLC25A3, TMEM176A, TMEM59 +1 more | View in SCUBA |
| Macrophages | MHC-II Antigen Presentation Innate immunity | AIF1, B2M, C1QA, C1QB, C1QC, CD68, CD74, CST3 +19 more | View in SCUBA |
| Pericytes | BMP-Stromal Signaling Developmental | BMP4, CXCL14, F3, MMP2, NBL1, PDGFRA, POSTN, TMEM176A | View in SCUBA |
| Smooth muscle cells | Matrisome Regulators ECM remodeling | ITM2C, LPP, LUM, NBL1, PMP22, S100A13, TCEAL4, TIMP2 +1 more | View in SCUBA |
About the gene
| Synonyms | LR8, MS4B2 |
|---|---|
| Chromosome | 7: 150791285-150801360 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
| Biological process | Differentiation |
Function
May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.