CXCR5 — C-X-C motif chemokine receptor 5
CXCR5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CXCR5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Tfh program B cell help | BAZ2B, CCDC50, CDK5R1, IL6R, LY96, MTUS1, PASK, PIP4P2 +10 more | View in SCUBA |
About the gene
| Synonyms | BLR1, CD185, MDR15 |
|---|---|
| Chromosome | 11: 118883892-118897787 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, G-protein coupled receptors, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
| Biological process | B-cell activation |
Function
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.