CYB5D1 — Cytochrome b5 domain containing 1
CYB5D1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CYB5D1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | NF-kB activation TCR/AP1/NFKb pathway | ADRA2B, CD83, CHD4, DUSP2, EGR2, EGR3, EGR4, FOSL1 +9 more | View in SCUBA |
| Macrophages | NF-κB Effector Response Inflammatory | ARL5B, BIRC3, DUSP2, EGR3, HES1, ICAM4, PTGS2, SIK1 | View in SCUBA |
| Neutrophils | Heat Shock Response Stress | ATP6V0C, DNAJA1, DUSP2, GNG10, HMOX1, HSP90AA1, HSP90AB1, HSPA1A +4 more |
About the gene
| Synonyms | FLJ32499 |
|---|---|
| Chromosome | 17: 7857746-7862282 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins |
Function
Radial spoke stalk protein that binds heme under oxidizing conditions. Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.