DDX52 — DExD-box helicase 52
DDX52 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DDX52's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | RNA Processing Housekeeping Housekeeping | CISD3, CNIH4, DPH3, EXOSC6, FABP5, GTF2E2, IKBKE, LYSET +20 more | View in SCUBA |
About the gene
| Synonyms | ROK1 |
|---|---|
| Chromosome | 17: 37609739-37643446 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Enzymes, Essential proteins, Predicted intracellular proteins |
| Molecular function | Helicase, Hydrolase, RNA-binding |
Function
Required for efficient ribosome biogenesis (By similarity). May control cell cycle progression by regulating translation of mRNAs that contain a terminal oligo pyrimidine (TOP) motif in their 5' UTRs, such as GTPBP4 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.