CNIH4 — Cornichon family AMPA receptor auxiliary protein 4
CNIH4 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNIH4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | ER-Golgi Trafficking Protein processing & ER | ALG5, HDDC3, KDELR1, ORMDL2, PYCARD, RAB8A, RASAL3, RBM42 +4 more | View in SCUBA |
| Endothelial | Nuclear Transport Housekeeping | ALYREF, BANF1, COX8A, HAUS1, HMGN1, ILF2, LSM5, MRPL51 +8 more | View in SCUBA |
| Macrophages | RNA Processing Housekeeping Housekeeping | CISD3, DDX52, DPH3, EXOSC6, FABP5, GTF2E2, IKBKE, LYSET +20 more | View in SCUBA |
| Monocytes | Inflammatory Monocyte Activation Inflammatory | ALDOA, C11orf98, CLEC2B, CRIP1, GRINA, IFITM2, LEPROTL1, NBPF26 +5 more | View in SCUBA |
About the gene
| Synonyms | HSPC163 |
|---|---|
| Chromosome | 1: 224356858-224379459 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | ER-Golgi transport, Protein transport, Transport |
Function
Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.