DEGS2 — Delta 4-desaturase, sphingolipid 2
DEGS2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DEGS2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | Lymphatic Valve Identity Valve formation | ALCAM, C12orf57, C17orf58, CFH, CLDN11, EBPL, EDNRB, GJA4 +13 more | View in SCUBA |
About the gene
| Synonyms | C14orf66, DES2, FADS8 |
|---|---|
| Chromosome | 14: 100143957-100159645 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Oxidoreductase |
| Biological process | Lipid biosynthesis, Lipid metabolism |
Function
Bifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.