DNAAF1 — Dynein axonemal assembly factor 1
DNAAF1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DNAAF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Integrin-mediated Migration Migration & adhesion | EIF4E, ITGA5, ITGB8, LMNA, MSC, NRIP3, PHLDA1, PNP +7 more | View in SCUBA |
About the gene
| Synonyms | CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt |
|---|---|
| Chromosome | 16: 84145287-84178767 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.