EGFLAM — EGF like, fibronectin type III and laminin G domains
EGFLAM belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EGFLAM's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Pericytes | Pericyte Identity Cytoskeletal | ABCC9, ARHGAP42, ARHGEF17, ECM2, EDNRA, GJC1, LHFPL6, MYO1B +2 more | View in SCUBA |
About the gene
| Synonyms | AGRINL, AGRNL, FLJ39155, PIKA |
|---|---|
| Chromosome | 5: 38258409-38465480 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted secreted proteins |
Function
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.