ARHGEF17 — Rho guanine nucleotide exchange factor 17
ARHGEF17 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGEF17's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Quiescent HSC State Stemness | BAALC, BIN1, CD52, GNAI1, HOPX, MZB1, RBPMS, SPINK2 | |
| Pericytes | Pericyte Identity Cytoskeletal | ABCC9, ARHGAP42, ECM2, EDNRA, EGFLAM, GJC1, LHFPL6, MYO1B +2 more | View in SCUBA |
About the gene
| Synonyms | KIAA0337, p164-RhoGEF, TEM4 |
|---|---|
| Chromosome | 11: 73308276-73369388 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Guanine-nucleotide releasing factor |
Function
Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.