GJC1 — Gap junction protein gamma 1
GJC1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GJC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | SPP1 Inflammatory Activation Inflammation | ADAM15, ATG4A, C1orf54, C7orf50, C9orf40, CPXM2, EBF3, EIF2AK4 +9 more | View in SCUBA |
| Pericytes | Pericyte Identity Cytoskeletal | ABCC9, ARHGAP42, ARHGEF17, ECM2, EDNRA, EGFLAM, LHFPL6, MYO1B +2 more | View in SCUBA |
| Smooth muscle cells | Notch-TGFbeta Signaling Development | ACKR3, AFAP1L2, CSRNP3, HTR1F, JAG1, LRRC10B, RAP2A, SLC38A11 +3 more | View in SCUBA |
About the gene
| Synonyms | CX45, GJA7 |
|---|---|
| Chromosome | 17: 44798448-44830816 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.