ARHGAP42 — Rho GTPase activating protein 42
ARHGAP42 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP42's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Pericytes | Pericyte Identity Cytoskeletal | ABCC9, ARHGEF17, ECM2, EDNRA, EGFLAM, GJC1, LHFPL6, MYO1B +2 more | View in SCUBA |
| Smooth muscle cells | SMC Phenotype Regulation Development | BMPR2, CTXN1, EFR3A, FAM20B, HACD4, INPP5A, OSBPL1A, RCSD1 +5 more | View in SCUBA |
About the gene
| Synonyms | AD031, FLJ32810, GRAF3, TMEM133 |
|---|---|
| Chromosome | 11: 100687288-100993941 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | GTPase activation |
Function
May influence blood pressure by functioning as a GTPase- activating protein for RHOA in vascular smooth muscle
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.