EPB41L4B — Erythrocyte membrane protein band 4.1 like 4B
EPB41L4B belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EPB41L4B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Fatty Acid Oxidation Mitochondrial & OxPhos | ACADVL, AK3, CAPNS1, ELOVL1, ESRP1, ESRRA, FUCA1, GLTP +11 more | View in SCUBA |
About the gene
| Synonyms | EHM2, LULU2 |
|---|---|
| Chromosome | 9: 109171974-109321059 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid- induced cell differentiation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.