SCUBA

ESF1 — ESF1 nucleolar pre-rRNA processing protein homolog

ESF1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ESF1's module in each cell type

Cell typeModuleShares the module with
Innate lymphoid cellsEndosomal Trafficking
Protein processing & ER
ARL14EP, CCDC90B, CLINT1, MDFIC, MDM4, MPHOSPH8, NRIP1, NSA2 +11 moreView in SCUBA

About the gene

SynonymsbA526K24.1, C20orf6
Chromosome20: 13714322-13784919
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins
Biological processTranscription, Transcription regulation

Function

May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.