CLINT1 — Clathrin interactor 1
CLINT1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLINT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Transit-amplifying progenitor Epithelial development | CCND2, EHF, ELOVL6, HSD17B12, MSI2, PKP2, RBM3, SLC38A1 | View in SCUBA |
| Gamma-delta T cells | Translation & Proteostasis RNA processing & translation | ARAP2, ATG13, BRPF1, CRKL, E2F3, EEF2, EIF2AK2, EIF2S3 +15 more | |
| Innate lymphoid cells | Endosomal Trafficking Protein processing & ER | ARL14EP, CCDC90B, ESF1, MDFIC, MDM4, MPHOSPH8, NRIP1, NSA2 +11 more | View in SCUBA |
| Neutrophils | Endocytic Vesicular Trafficking Vesicular traficking | DNAJC13, LNPK, PHACTR2, PRAM1, PRKAA1, PTPN22, SEC63, VCL |
About the gene
| Synonyms | CLINT, ENTH, EPNR, KIAA0171 |
|---|---|
| Chromosome | 5: 157785743-157859145 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Transporters |
| Biological process | Endocytosis |
Function
Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.