NSA2 — NSA2 ribosome biogenesis factor
NSA2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NSA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Oxidative Phosphorylation Mitochondrial & OxPhos | ANP32B, ATP5MC2, C19orf53, COX7C, EIF3H, EIF3M, EMC7, GPX4 +10 more | View in SCUBA |
| Gamma-delta T cells | Translation Initiation RNA processing & translation | BTF3, C12orf57, COMMD6, COX4I1, COX7C, EEF1B2, EEF1D, EEF1G +18 more | |
| Innate lymphoid cells | Endosomal Trafficking Protein processing & ER | ARL14EP, CCDC90B, CLINT1, ESF1, MDFIC, MDM4, MPHOSPH8, NRIP1 +11 more | View in SCUBA |
| Macrophages | Translation Initiation Housekeeping | AKR1B1, CAMLG, CAPZB, EEF1D, EEF2, EID1, EIF3D, EIF3E +26 more | View in SCUBA |
| Mucosal-associated invariant T cell | Antigen Processing Protein processing & ER | AQP3, ATP5MJ, CAPNS1, CCDC107, CTDNEP1, NCR3, PHB2, PPA1 +8 more |
About the gene
| Synonyms | FLJ94393, HCLG1, HUSSY-29, TINP1 |
|---|---|
| Chromosome | 5: 74766991-74780113 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins |
| Molecular function | Ribonucleoprotein |
| Biological process | Ribosome biogenesis, rRNA processing |
Function
Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.