ETV7 — ETS variant transcription factor 7
ETV7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ETV7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Th1 IL12 response Immune regulation | ADCY3, AKIRIN2, CTNNA1, HIVEP3, IL12RB2, JAKMIP1, PTPN1, RFTN1 +2 more | View in SCUBA |
| Monocytes | IFN-gamma Response Antiviral | APOL2, APOL6, CXCL10, GBP1, GBP4, GBP5, IFIH1, ISG15 +6 more | View in SCUBA |
About the gene
| Synonyms | TEL-2, TEL2 |
|---|---|
| Chromosome | 6: 36354091-36387800 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.