SCUBA

FBXO21 — F-box protein 21

FBXO21 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FBXO21's module in each cell type

Cell typeModuleShares the module with
FibroblastsLysosomal Cytoskeletal
Vesicular traficking
C7orf50, LHFPL6, MAGED2, PLS3, PPT1, SCPEP1, SDC2, TTC3 +1 moreView in SCUBA

About the gene

SynonymsFBX21, KIAA0875
Chromosome12: 117141991-117190470
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processUbl conjugation pathway

Function

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.