SDC2 — Syndecan 2
SDC2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SDC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Lysosomal Cytoskeletal Vesicular traficking | C7orf50, FBXO21, LHFPL6, MAGED2, PLS3, PPT1, SCPEP1, TTC3 +1 more | View in SCUBA |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ANPEP, AQP9, CD300E, CD82, CLEC5A, CXXC5, DDX60L, DHRS9 +25 more | View in SCUBA |
| Monocytes | SPP1+ Inflammatory Macrophage Inflammatory | DOCK4, DUSP4, FLT1, GPR137B, IL7R, INHBA, MMP14, NECTIN2 +6 more | View in SCUBA |
| Pericytes | Pericyte ECM Production ECM production | AEBP1, CALD1, COL14A1, GUCY1B1, LURAP1L, PMP22, TPPP3, VCL | View in SCUBA |
| Smooth muscle cells | OxPhos & proteasome Mitochondrial & OxPhos | CD151, CHCHD2, COX5B, EID1, NDUFA11, NDUFB2, NDUFB9, NEDD8 +8 more | View in SCUBA |
About the gene
| Synonyms | CD362, fibroglycan, HSPG, HSPG1, SYND2 |
|---|---|
| Chromosome | 8: 96493813-96611790 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted membrane proteins |
| Biological process | Differentiation, Neurogenesis |
Function
Cell surface proteoglycan which regulates dendritic arbor morphogenesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.