PLS3 — Plastin 3
PLS3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLS3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Angiogenic Activation Inflammation | ALPL, APOL4, ASAP2, CALM1, COMMD2, FAT4, PDGFB, RALGAPA1 +4 more | View in SCUBA |
| Fibroblasts | Lysosomal Cytoskeletal Vesicular traficking | C7orf50, FBXO21, LHFPL6, MAGED2, PPT1, SCPEP1, SDC2, TTC3 +1 more | View in SCUBA |
| Pericytes | Caveolae Organization Cytoskeletal | CAV1, CAV2, CAVIN1, PDLIM5, PLEC, SYNE2, UTRN | View in SCUBA |
| Smooth muscle cells | Actin remodeling Cytoskeletal | ARPC5, CALM1, GADD45GIP1, GNAS, HNRNPM, KTN1, SERBP1 | View in SCUBA |
About the gene
| Synonyms | T-plastin |
|---|---|
| Chromosome | X: 115561174-115650861 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Actin-bundling protein
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.