SCPEP1 — Serine carboxypeptidase 1
SCPEP1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SCPEP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | ER/vesicle trafficking Protein processing & ER | ATP6V0B, CD99, DIAPH1, HCST, M6PR, MTDH, MTPN, REEP5 +1 more | View in SCUBA |
| Fibroblasts | Lysosomal Cytoskeletal Vesicular traficking | C7orf50, FBXO21, LHFPL6, MAGED2, PLS3, PPT1, SDC2, TTC3 +1 more | View in SCUBA |
| Hematopoietic progenitor cells | ILC/NK Development Lymphcyte development | ACY3, ADGRD1, ATP10A, CCDC141, CD3E, CYSLTR1, ID2, ITGB7 +7 more | |
| Innate lymphoid cells | ILC3 identity Differentiation | ABCC1, BCL6, CCND3, CELF2, CHKB, DNAAF2, ENSG00000285976, EREG +31 more | View in SCUBA |
| Macrophages | Oxidative Metabolic Program Mitochondrial & OxPhos | ACADM, CA2, CALM3, CAPG, COQ2, CSRP1, CSTB, DENND2D +29 more | View in SCUBA |
| Smooth muscle cells | Sparse Mitoribosomal Housekeeping Housekeeping | CEP63, CIB1, CTNNA1, ERGIC3, FBXO17, LEPROT, MRPL32, MRPL41 +6 more | View in SCUBA |
About the gene
| Synonyms | RISC |
|---|---|
| Chromosome | 17: 56978129-57006768 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Carboxypeptidase, Hydrolase, Protease |
Function
May be involved in vascular wall and kidney homeostasis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.