MAGED2 — MAGE family member D2
MAGED2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MAGED2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Lysosomal Cytoskeletal Vesicular traficking | C7orf50, FBXO21, LHFPL6, PLS3, PPT1, SCPEP1, SDC2, TTC3 +1 more | View in SCUBA |
| Gamma-delta T cells | Lysosomal Biogenesis Protein processing & ER | ABI3, APLP2, ATP10A, B3GALT4, BAX, CD63, CTNNA1, DOCK5 +14 more | |
| Glial cells | Antioxidant Stress Response Stress | AP2S1, CSTB, DYNLRB1, HSBP1, NDUFB11, PLPP1, PPDPF, SELENOW +1 more | View in SCUBA |
| Smooth muscle cells | Ribonucleoprotein & translation RNA processing & translation | CRYAB, CYB5R3, EEF1B2, HMGB1, HNRNPC, LAPTM4A, NACA, NCL +5 more | View in SCUBA |
About the gene
| Synonyms | 11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386 |
|---|---|
| Chromosome | X: 54807599-54816015 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Tumor antigen |
Function
Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.