FGFBP1 — Fibroblast growth factor binding protein 1
FGFBP1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FGFBP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Chromatin Transcriptional Control chromatin regulation & transcription | ARIH1, DSP, KDM6B, KHDC4, KIAA0040, MNT, PABPN1, PHLDA2 +6 more | View in SCUBA |
About the gene
| Synonyms | FGFBP, HBP17 |
|---|---|
| Chromosome | 4: 15935577-15938740 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted secreted proteins |
| Molecular function | Growth factor binding |
Function
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.