KHDC4 — KH domain containing 4, pre-mRNA splicing factor
KHDC4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KHDC4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Transcriptional Repression Housekeeping | AKAP8, ANKRD11, ARIH2, BACH1, CCNT2, CDK13, CEP95, CSNK1D +23 more | View in SCUBA |
About the gene
| Synonyms | BLOM7, KIAA0907, SNORA80EHG |
|---|---|
| Chromosome | 1: 155913045-155934413 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.