MNT — MAX network transcriptional repressor
MNT belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MNT's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Chromatin Transcriptional Control chromatin regulation & transcription | ARIH1, DSP, FGFBP1, KDM6B, KHDC4, KIAA0040, PABPN1, PHLDA2 +6 more | View in SCUBA |
About the gene
| Synonyms | bHLHd3, lncRNA-HAL, MAD6, MXD6, ROX |
|---|---|
| Chromosome | 17: 2384073-2401104 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.