FOXL1 — Forkhead box L1
FOXL1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FOXL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Myofibroblast Subtype Wound healing | EDNRB, HACD4, KCTD9, MGLL, PDGFD, POSTN, TSPAN33, ZEB1 | View in SCUBA |
About the gene
| Synonyms | FKH6, FKHL11, FREAC7 |
|---|---|
| Chromosome | 16: 86576368-86583478 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 and GLI3 transcription factors (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.