KCTD9 — Potassium channel tetramerization domain containing 9
KCTD9 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KCTD9's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Myofibroblast Subtype Wound healing | EDNRB, FOXL1, HACD4, MGLL, PDGFD, POSTN, TSPAN33, ZEB1 | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing Regulation RNA processing & translation | ARF6, BTG3, CAPN7, CDV3, CELF2, CNBD2, CUL3, CYTIP +18 more | |
| Macrophages | Central Carbon Metabolism Housekeeping | ACLY, ACO2, CBFB, CSK, DARS1, DLD, DPAGT1, EMC1 +19 more | View in SCUBA |
About the gene
| Synonyms | BTBD27, FLJ20038 |
|---|---|
| Chromosome | 8: 25427847-25458476 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Ubl conjugation pathway |
Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.