HAPLN2 — Hyaluronan and proteoglycan link protein 2
HAPLN2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HAPLN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | Actomyosin Regulation Contractility | ARID5A, ASAH1, CAP2, COX6A2, DMTN, GABRA4, NAPA, NMRK2 +6 more | View in SCUBA |
About the gene
| Synonyms | BRAL1 |
|---|---|
| Chromosome | 1: 156619331-156625725 |
| Predicted location | Secreted |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted secreted proteins |
Function
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.