NAPA — NSF attachment protein alpha
NAPA belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NAPA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Type I Interferon Inflammation | BST2, CHMP5, EIF2AK2, LAP3, NMI, OASL, PLSCR1, SPATS2L +1 more | View in SCUBA |
| Gamma-delta T cells | TGF-beta Signaling Immune regulation | ABCF1, ABHD12, ACAP2, ADIPOR2, CBX6, ENPP4, FBXO9, GSAP +18 more | |
| Macrophages | Antiviral ISG Response Antiviral | ADAR, APOL6, ARID5A, CLEC7A, DDX60, DTX3L, EIF2AK2, ERICH1 +29 more | View in SCUBA |
| Smooth muscle cells | Actomyosin Regulation Contractility | ARID5A, ASAH1, CAP2, COX6A2, DMTN, GABRA4, HAPLN2, NMRK2 +6 more | View in SCUBA |
About the gene
| Chromosome | 19: 47487637-47515091 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | ER-Golgi transport, Protein transport, Transport |
Function
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.