HPDL — 4-hydroxyphenylpyruvate dioxygenase like
HPDL belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HPDL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Crypt Colonocyte Identity Epithelial development | AQP1, ARAP3, ATP2C2, BIN1, BTG3, CDCA7, CEP68, CNFN +36 more | View in SCUBA |
About the gene
| Synonyms | 4-HPPD-L, GLOXD1, MGC15668 |
|---|---|
| Chromosome | 1: 45326895-45328710 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Dioxygenase, Oxidoreductase |
Function
Iron-dependent dioxygenase that catalyzes the conversion of 4-hydroxyphenylpyruvate (4-HPPA) to 4-hydroxymandelate (4-HMA) in the mitochondria, one of the steps in the biosynthesis of coenzyme Q10 from tyrosine
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.