CDCA7 — Cell division cycle associated 7
CDCA7 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDCA7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | G1/S Replication Cell cycle | CHAF1A, CHEK1, E2F1, HELLS, MCM2, MCM4, MCM6, MSH2 +3 more | View in SCUBA |
| CD4⁺ T cells | MHC-II antigen presentation Immune regulation | CD74, CHN1, FABP5, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA +3 more | View in SCUBA |
| CD8⁺ T cells | MCM Helicase Loading Cell cycle | CDC45, DCTPP1, E2F1, GINS2, HELLS, MCM2, MCM3, MCM4 +5 more | View in SCUBA |
| Goblet cells | Anti-inflammatory Lipid Signaling Housekeeping | AQP1, FBL, IMPDH2, PRDX5, PTGDR, RARRES2, UGT2A3 | View in SCUBA |
About the gene
| Synonyms | FLJ14736, JPO1 |
|---|---|
| Chromosome | 2: 173354820-173368997 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | Apoptosis, Transcription, Transcription regulation |
Function
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.