BTG3 — BTG anti-proliferation factor 3
BTG3 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BTG3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Chromatin Regulation DNA/chromatin regulation | ADI1, ASXL2, CASP8, CHD3, CTSS, CWF19L2, DENND2D, DNTTIP2 +17 more | View in SCUBA |
| Fibroblasts | ER Stress UPR Stress | ARF4, B4GALT1, BZW1, CYCS, EFHD2, ELOC, LDHA, LITAF +6 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing Regulation RNA processing & translation | ARF6, CAPN7, CDV3, CELF2, CNBD2, CUL3, CYTIP, ELF1 +18 more | |
| Glial cells | Inflammatory Cytokine Signaling Inflammation | BACH1, CSF1, FSTL3, NNMT, PAPPA, PDPN, RAB13, STK17A +3 more | View in SCUBA |
| Macrophages | G1/S Transition Cell cycle | ARL6IP6, CNOT9, HAT1, HAUS2, PAICS, SFXN1, SLBP, SLC7A1 +1 more | View in SCUBA |
| Monocytes | Inflammatory Cell Death Inflammatory | ARL4C, CD63, HIC1, MFSD2A, NINJ1, PID1, SNN, TRIP10 | View in SCUBA |
| Mucosal-associated invariant T cell | mRNA Decay Program RNA processing & translation | ATP6V0C, BCL7B, BTG1, CCDC59, DDIT4, DUSP2, DYNLL2, EXOSC6 +13 more |
About the gene
| Synonyms | ANA, ANA/BTG3, APRO4, tob55 |
|---|---|
| Chromosome | 21: 17593653-17612945 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.