LNPK — Lunapark, ER junction formation factor
LNPK belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LNPK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Central Carbon Metabolism Housekeeping | ACLY, ACO2, CBFB, CSK, DARS1, DLD, DPAGT1, EMC1 +19 more | View in SCUBA |
| Neutrophils | Endocytic Vesicular Trafficking Vesicular traficking | CLINT1, DNAJC13, PHACTR2, PRAM1, PRKAA1, PTPN22, SEC63, VCL |
About the gene
| Synonyms | KIAA1715, LNP, LNP1, Ul |
|---|---|
| Chromosome | 2: 175923882-176002839 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | Developmental protein |
Function
Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb development (By similarity). Is involved in central nervous system development.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.