NMT1 — N-myristoyltransferase 1
NMT1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NMT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Mucosal-associated invariant T cell | Cellular Housekeeping Housekeeping | AKR7A2, ANP32A, ANXA5, AP1M1, APEX1, APOBEC3C, CDC26, DBNL +17 more |
About the gene
| Synonyms | NMT |
|---|---|
| Chromosome | 17: 44957992-45109016 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Acyltransferase, Transferase |
Function
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.